Hydrochloric Acid → HCID 68782182, compound

Participants

Reaction Steps

A solution of 4-(5-pyridin-3-yl-pyrimidin-2-ylamino)-piperidine-1-carboxylic acid tert-butyl ester (0.68 g, 1.91 mmol) in 4 M HCl in dioxane (40 mL) was stirred at rt for 2 h. The solvent was removed under reduced pressure and the crude product used in the consecutive step without further purification assuming quantitative deprotection and formation of the dihydrochloride salt. MS (ISP): 256.5 [M+H]+.

Provenance & Evidence