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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2264563Generated: October 25, 2026

5-((6-Chloropyrimidin-4-yl)oxy)-1H-indole → 5-[(2-chloro-4-pyrimidinyl)oxy]-2,3-dihydro-1H-indole

https://huagongshe.com/reaction/2264563

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-((6-Chloropyrimidin-4-yl)oxy)-1H-indoleHCID 57455156—
Reactant5-(2-chloropyrimidin-4-yloxy)-1H-indoleHCID 57737346—
Product5-[(2-chloro-4-pyrimidinyl)oxy]-2,3-dihydro-1H-indoleHCID 86618285—

Reaction Steps

Utilising a similar procedure, but employing 5-[(2-chloro-4-pyrimidinyl)oxy]-1H-indole in lieu of 5-[(6-chloro-4-pyrimidinyl)oxy]-1H-indole afforded 5-[(2-chloro-4-pyrimidinyl)oxy]-2,3-dihydro-1H-indole, as an oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07855215B2
Source datasetuspto-grants-2010_12
ORD IDord-abc28d08649e4a51996233c8249f7559
Source noteuspto-grants-2010_12