Tert-butyl {2-[3-(benzyloxy)phenyl]ethyl}carbamate → tert-Butyl 3-hydroxyphenethylcarbamate

Participants

Reaction Steps

1 g of Pd/C 10% was added to a solution of 13 g (0.039 mol) of [2-(3-benzyloxy-phenyl)ethyl]-carbamic acid tert-butyl ester in 100 ml of ethanol. The mixture was hydrogenated at 40 psi overnight. The catalyst was filtered off and washed with ethanol. The solvent was removed under vacuum and 9.4 g of the title compound were obtained as a colourless oil in quantitative yield.

Provenance & Evidence