3-Pyridinylboronic acid → HCID 24874607, compound

Participants

Reaction Steps

The title compound was prepared as described in Example 78 (Scheme #14, N) using pyridin-3-ylboronic acid and 1-(3-bromophenyl)-6-fluoro-1-pyridin-4-yl-1H-isoindol-3-amine (Example 82) (18.5% yield): 1H NMR (DMSO-d6) δ 8.77 (m, 1 H), 8.55 (dd, J=4.80, 1.52 Hz, 1 H), 8.46 (m, 2 H), 7.95 (m, 1 H), 7.87-7.81 (m, 2 H), 7.59 (m, 2 H), 7.47 (m, 1 H), 7.39-7.44 (m, 2 H), 7.37-7.31 (m, 3 H), 6.96 (br s, 2 H); MS (ESI) m/z 381 [M+1]+.

Provenance & Evidence