(Pyrimidin-5-yl)boronic acid → HCID 24874608, compound

Participants

Reaction Steps

The title compound was prepared as described in Example 78 (Scheme #14, N) using pyrimidin-5-ylboronic acid and 1-(3-bromophenyl)-6-fluoro-1-pyridin-4-yl-1H-isoindol-3-amine (Example 82) (26% yield): 1H NMR (CDCl3) δ 9.19 (s, 1 H), 8.87 (s, 2 H), 8.55 (m, 2 H), 7.53-7.45 (m, 4 H), 7.36 (m, 1 H), 7.29-7.25 (m, 3 H), 7.20 (m, 1 H); MS (ESI) m/z 382 [M+1]+.

Provenance & Evidence