5-Methoxypyridine-3-boronic Acid → HCID 24874609, compound

Participants

Reaction Steps

The title compound was prepared as described in Example 78 (Scheme #14, N) using (5-methoxypyridin-3-yl)boronic acid and 1-(3-bromophenyl)-6-fluoro-1-pyridin-4-yl-1H-isoindol-3-amine (Example 82) (16% yield): 1H NMR (CDCl3) δ 8.54 (m, 2 H), 8.36 (d, J=1.77 Hz, 1 H), 8.28 (d, J=2.78 Hz, 1 H), 7.52-7.45 (m, 3 H), 7.42 (m, 1 H), 7.32-7.25 (m, 5 H), 7.18 (m, 1 H), 3.90 (s, 3 H); MS (ESI) m/z 411 [M+1]+.

Provenance & Evidence