2-Fluoropyridine-3-boronic acid → HCID 24874610, compound

Participants

Reaction Steps

The title compound was prepared as described in Example 78 (Scheme #14, N) using (2-fluoropyridin-3-yl)boronic acid and 1-(3-bromophenyl)-6-fluoro-1-pyridin-4-yl-1H-isoindol-3-amine (Example 82) (22.5% yield): 1H NMR (CDCl3) δ 8.54 (m, 2 H), 8.18 (m, 1 H), 7.79 (m, 1 H), 7.50 (m, 1 H), 7.48-7.39 (m, 3 H), 7.32 (m, 1 H), 7.29-7.23 (m, 4 H), 7.18 (m, 1 H); MS (ESI) m/z 399 [M+1]+.

Provenance & Evidence