3,5-Dichlorophenylboronic acid → HCID 24874644, compound

Participants

Reaction Steps

The title compound was prepared as described for Example 78 (Scheme #14, N) starting from 1-(3-bromophenyl)-1-(4-methoxyphenyl)-1H-isoindole-3-amine acetate (Example 87) and (3,5-dichlorophenyl)boronic acid in 28% yield: 1H NMR (DMSO-d6) δ 7.78-7.74 (m, 2 H), 7.59-7.52 (m, 5 H), 7.47-7.41 (m, 2 H), 7.41-7.34 (m, 2 H), 7.23-7.18 (m, 2 H), 6.82-6.77 (m, 2 H), 3.69 (s, 3 H), 1.88 (s, 3 H); MS (ES) m/z 459, 461, 463 [M+1]+.

Provenance & Evidence