2-Fluoropyridine-3-boronic acid → HCID 24874782, compound

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Reaction Steps

The title compound was synthesized from 1-(3-bromophenyl)-1-(2-fluoropyridin-4-yl)-1H-isoindol-3-amine (Example 116) as described in Example 67 Scheme #10, D in 19% yield using 2-fluoropyridine-3-boronic acid. 1H NMR (DMSO-d6) δ 8.26-8.19 (m, 1 H), 8.15 (d, J=5.31 Hz, 1 H), 8.08-7.99 (m, 1 H), 7.95-7.79 (m, 2 H), 7.59-7.38 (m, 7 H), 7.37-7.30 (m, 1 H), 7.18-6.82 (m, 3 H); MS (ESI) m/z 399 [M+1]+.

Provenance & Evidence