2-Fluoropyridine-3-boronic acid → HCID 24874783, compound

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Reaction Steps

The title compound was synthesized from 1-(3-bromophenyl)-1-(2-methoxypyridin-4-yl)-1H-isoindol-3-amine (Example 118) as described in Example 67 Scheme #10, D in 23% yield using 2-fluoropyridine-3-boronic acid. 1H NMR (DMSO-d6) δ 8.20-8.26 (m, 1 H), 7.97-8.09 (m, 2 H), 7.75-7.92 (m, 2 H), 7.37-7.58 (m, 7 H), 6.78-7.10 (m, 3 H), 6.67 (s, 1 H), 3.79 (s, 3 H); MS (ESI) m/z 411 [M+1]+.

Provenance & Evidence