2-Fluoropyridine-3-boronic acid → HCID 24874822, compound

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Reaction Steps

The title compound was synthesized from 1-(3-bromophenyl)-1-(5-fluoropyridin-3-yl)-1H-isoindol-3-amine (Example 123) as described in Example 67 Scheme #10, D in 26% yield using 2-fluoropyridine-3-boronic acid. 1H NMR (DMSO-d6) δ 8.35-8.45 (m, 2 H), 8.12-8.21 (m, 1 H), 7.92-8.01 (m, 1 H), 7.83-7.90 (m, 1 H), 7.73-7.82 (m, 1 H), 7.33-7.56 (m, 8 H), 6.91 (br s, 2 H); MS (ESI) m/z 399 [M+1]+.

Provenance & Evidence