HCID 59596697, compound → HCID 59596666, compound

Participants

Reaction Steps

A suspension of methyl (2S)-5-(3-cyano-4-{[(2-fluorophenyl)methyl]oxy}phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate (D72, 70 mg, 0.198 mmol) and Pt (5% on carbon) in ethyl acetate (10 ml) was stirred at room temperature for 24 hrs. Filtration over celite and subsequent evaporation gave the title compound (64 mg, 91%). The obtained material was used unpurified in the next step. UPLC: Rt=0.55 min, MS: (ES/+) m/z: 355 [MH+], C20H19FN2O3 requires 354.

Provenance & Evidence