4-Methylquinoline → 1-(4-Acetoxybutyl)-4-methyl-chinolinium iodide

HRID 2264861Notes

Reaction equation

HRID 2264861 reaction equation
[N:1]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:4]([CH3:5])=[CH:3][CH:2]=1.[I:12][CH2:13][CH2:14][CH2:15][CH2:16][O:17][C:18](=[O:20])[CH3:19]>CCOCC>[I-:12].[C:18]([O:17][CH2:16][CH2:15][CH2:14][CH2:13][N+:1]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:4]([CH3:5])=[CH:3][CH:2]=1)(=[O:20])[CH3:19]

Participants

4

Reactant 2

HCID 102854-MethylquinolineHCID 27334054-Iodobutyl acetate

Product 1

HCID 687836491-(4-Acetoxybutyl)-4-methyl-chinolinium iodide

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

10 mmol (1.43 g) lepidine and 10 mmol (2.42 g) 4-iodobutylacetate are heated 4 h at 120° C. and after cooling repeatedly stirred with ether, decanted a finally dried in vacuum.

Workup

  1. temperatureafter cooling repeatedly
  2. customdecanted
  3. customa finally dried in vacuum

Sources & evidence

ORD record
ord-898c7f10ee0c4e3085ba134c7e37e15d
Source dataset
uspto-grants-2010_12
Patent number
US07855293B2

Reaction notes

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