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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2265087Generated: October 28, 2026

Ethyl 3-(4-aminophenyl)acrylate → Ethyl 4-[[3,5-bis(trimethylsilyl)benzoyl]amino]cinnamate

https://huagongshe.com/reaction/2265087

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 3-(4-aminophenyl)acrylateHCID 97826—
Reactant(E)-Ethyl 3-[6-[[3,5-bis(trimethylsilyl)benzoyl]amino]pyridin-3-yl]acrylateHCID 86644273—
ProductEthyl 4-[[3,5-bis(trimethylsilyl)benzoyl]amino]cinnamateHCID 6848756962%

Reaction Steps

Using BTMB (10.0 g) and ethyl 4-aminocinnamate (8.62 g), Compound 3a (10.3 g, 62%) was obtained as a yellow solid in the same manner as Compound 1b was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07855300B2
Source datasetuspto-grants-2010_12
ORD IDord-4635d42b7e51473ea5f01bfead313f22
Source noteuspto-grants-2010_12