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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2265095Generated: October 28, 2026

4-Bromo-3-chloroaniline → Ethyl 4-amino-2-chlorocinnamate

https://huagongshe.com/reaction/2265095

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-3-chloroanilineHCID 88888—
ReactantEthyl 3-(4-amino-2-fluorophenyl)prop-2-enoateHCID 53987187—
ProductEthyl 4-amino-2-chlorocinnamateHCID 5442596699%

Reaction Steps

Using 4-bromo-3-chloroaniline (5.0 g), Compound 8a (5.43 g, 99%) was obtained as a yellow solid in the same manner as Compound 2a was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07855300B2
Source datasetuspto-grants-2010_12
ORD IDord-643f750a782c4aaf93ba5a930e0fd406
Source noteuspto-grants-2010_12