HCID 25258036, compound → HCID 59446287, compound

Participants

Reaction Steps

Compound 14 (214 mg) was dissolved in tetrahydrofuran (4.0 ml) and methanol (4.0 ml), and a 10% palladium carbon catalyst (70.0 mg) was added thereto. The obtained mixture was stirred at room temperature in a hydrogen atmosphere for 6 hours. The catalyst was removed by Cerite filtration, and the solvent was distilled off from the filtrate under reduced pressure. As a result, Compound 16 (202 mg, 94%) was obtained as an opalescent solid.

Provenance & Evidence