3,5-Bis-trifluoromethylphenylboronic acid → 2-(5-Hydroxy-3',5'-bis-trifluoromethyl-biphenyl-3-yl)-4-methyl-pentanoic acid methyl ester

Participants

Reaction Steps

The title compound was prepared in 38% yield from 2-(3-benzyloxy-5-trifluoromethanesulfonyloxy-phenyl)-4-methyl-pent-4-enoic acid methyl ester (prepared in Example 15, step (d)) under the conditions described in Example 15, step (e-f) using 3,5-bis-trifluoromethylphenylboronic acid in step (e).

Provenance & Evidence