4-Chloro-2-(quinoxaline-5-sulfonylamino)benzoic acid → HCID 68772228, compound

HRID 2265185Notes

Reaction equation

HRID 2265185 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](O)=[O:7])=[C:4]([NH:11][S:12]([C:15]2[C:16]3[N:17]=[CH:18][CH:19]=[N:20][C:21]=3[CH:22]=[CH:23][CH:24]=2)(=[O:14])=[O:13])[CH:3]=1.Cl.[CH3:26][O:27][C:28](=[O:42])[C@@H:29]([NH2:41])[CH2:30][C:31]1[CH:40]=[CH:39][C:38]2[C:33](=[CH:34][CH:35]=[CH:36][CH:37]=2)[CH:32]=1>>[CH3:26][O:27][C:28](=[O:42])[C@@H:29]([NH:41][C:6](=[O:7])[C:5]1[CH:9]=[CH:10][C:2]([Cl:1])=[CH:3][C:4]=1[NH:11][S:12]([C:15]1[C:16]2[N:17]=[CH:18][CH:19]=[N:20][C:21]=2[CH:22]=[CH:23][CH:24]=1)(=[O:14])=[O:13])[CH2:30][C:31]1[CH:40]=[CH:39][C:38]2[C:33](=[CH:34][CH:35]=[CH:36][CH:37]=2)[CH:32]=1

Participants

3

Reactant 2

HCID 160907784-Chloro-2-(quinoxaline-5-sulfonylamino)benzoic acidHCID 56777259methyl (2S)-2-amino-3-(naphthalen-2-yl)propanoate hydrochloride

Product 1

HCID 68772228HCID 68772228, compound

Procedure

4-Chloro-2-(quinoxaline-5-sulfonylamino)benzoic acid was coupled with (S)-2-amino-3-naphthalen-2-yl-propionic acid methyl ester hydrochloride as in EXAMPLE 1, Part C.

Sources & evidence

ORD record
ord-1512230d3ef34be2a511d1a3d0cd55c6
Source dataset
uspto-grants-2010_12
Patent number
US07855292B2

Reaction notes

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