Methyl 4-chloroanthranilate → 2-(2,6-Difluoro-benzenesulfonylamino)-4-chloro-benzoic acid

HRID 2265218Notes

Reaction equation

HRID 2265218 reaction equation
[NH2:1][C:2]1[CH:11]=[C:10]([Cl:12])[CH:9]=[CH:8][C:3]=1[C:4]([O:6]C)=[O:5].[F:13][C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([F:20])[C:15]=1[S:21](Cl)(=[O:23])=[O:22]>>[F:13][C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([F:20])[C:15]=1[S:21]([NH:1][C:2]1[CH:11]=[C:10]([Cl:12])[CH:9]=[CH:8][C:3]=1[C:4]([OH:6])=[O:5])(=[O:23])=[O:22]

Participants

3

Reactant 2

HCID 80001Methyl 4-chloroanthranilateHCID 27342712,6-Difluorobenzenesulfonyl chloride

Product 1

HCID 687704442-(2,6-Difluoro-benzenesulfonylamino)-4-chloro-benzoic acid

Procedure

Methyl 2-amino-4-chlorobenzoate was sulfonylated with 2,6-difluorobenzenesulfonyl chloride and hydrolyzed as in EXAMPLE 1, Parts A and B.

Sources & evidence

ORD record
ord-79855a7e9e3140a4826b39a668497701
Source dataset
uspto-grants-2010_12
Patent number
US07855292B2

Reaction notes

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