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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 226528Generated: October 30, 2026

(3,5-Difluorophenyl)boronic acid → HCID 57754957, compound

https://huagongshe.com/reaction/226528

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3,5-Difluorophenyl)boronic acidHCID 2734338—
Reactant2-(5-Hydroxy-4'-trifluoromethyl-biphenyl-3-yl)-4-methyl-pentanoic acid methyl esterHCID 57754941—
ProductHCID 57754957HCID 5775495715%

Reaction Steps

The title compound was prepared in 15% yield from 2-(5-hydroxy-4′-trifluoromethyl-biphenyl-3-yl)-4-methyl-pentanoic acid methyl ester (prepared in Example 15, step (f)) and 3,5-difluorobenzeneboronic acid under the conditions described in Example 15, step (g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557244B2
Source datasetuspto-grants-2009_07
ORD IDord-b23d3b409fdd4f8387b54aca505bf8ad
Source noteuspto-grants-2009_07