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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 226530Generated: October 30, 2026

4-Chlorophenylboronic acid → HCID 57755033, compound

https://huagongshe.com/reaction/226530

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chlorophenylboronic acidHCID 74299—
Reactant2-(5-Hydroxy-4'-trifluoromethyl-biphenyl-3-yl)-4-methyl-pentanoic acid methyl esterHCID 57754941—
ProductHCID 57755033HCID 5775503335%

Reaction Steps

The title compound was prepared in 35% yield from 2-(5-hydroxy-4′-trifluoromethyl-biphenyl-3-yl)-4-methyl-pentanoic acid methyl ester (prepared in Example 15, step (f)) and 4-chlorobenzene boronic acid under the conditions described in Example 15, step (g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557244B2
Source datasetuspto-grants-2009_07
ORD IDord-c11e8840958c4e35948a6fed27413771
Source noteuspto-grants-2009_07