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HRID 2265323作成日：2026年10月25日

6-(Propan-2-yl)pyridin-3-amine → 5-benzyloxy-N-(6-isopropylpyridin-3-yl)-8-methyl-1,2,3,4-tetrahydronaphthalene-1-carboxamide

https://huagongshe.com/reaction/2265323

反応式

関与物質

役割名称HCID仕込み量
反応物6-(Propan-2-yl)pyridin-3-amineHCID 17854288—
反応物5-Benzyloxy-8-methyl-1,2,3,4-tetrahydronaphthalene-1-carboxylic acidHCID 17854502—
生成物5-benzyloxy-N-(6-isopropylpyridin-3-yl)-8-methyl-1,2,3,4-tetrahydronaphthalene-1-carboxamideHCID 1785432493.4%

反応手順

By the reaction and treatment in the same manner as in Preparation Example 18 using 5-benzyloxy-8-methyl-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (1.34 g) and 5-amino-2-isopropylpyridine (0.62 g) as starting materials, 5-benzyloxy-N-(6-isopropylpyridin-3-yl)-8-methyl-1,2,3,4-tetrahydronaphthalene-1-carboxamide (1.75 g) was obtained.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07855297B2
出典データセットuspto-grants-2010_12
ORD IDord-d15a2fcef0324978964f83022375a13a
出典メモuspto-grants-2010_12