3,4-Dihydro-2H-1-benzopyran-4-carboxylic acid → N-[(4-dimethylaminophenyl) methyl]-N-(4-isopropylphenyl)chroman-4-carboxamide

Participants

Role	Name	HCID	Charge
Reactant	3,4-Dihydro-2H-1-benzopyran-4-carboxylic acid	HCID 188669	—
Reactant	N-(4-(Dimethylamino)benzyl)-4-isopropylbenzenamine	HCID 21957887	—
Product	N-[(4-dimethylaminophenyl) methyl]-N-(4-isopropylphenyl)chroman-4-carboxamide	HCID 10159665	24.9%

Reaction Steps

By the reaction and treatment in the same manner as in Example 1 using chroman-4-carboxylic acid (0.5 g) and [(4-dimethylaminophenyl)methyl](4-isopropylphenyl)amine (0.63 g) as starting materials, N-[(4-dimethylaminophenyl) methyl]-N-(4-isopropylphenyl)chroman-4-carboxamide (0.25 g) was obtained. melting point: 110-112° C.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07855297B2
Source dataset	uspto-grants-2010_12
ORD ID	ord-3dbc54a329bb4868992aaa85061a1def
Source note	uspto-grants-2010_12