HCID 17854306, compound → HCID 10162195, compound

HRID 2265344Notes

Reaction equation

HRID 2265344 reaction equation
[CH:1]([C:4]1[CH:13]=[C:12]2[C:7]([CH2:8][CH2:9][CH2:10][CH:11]2[C:14]([OH:16])=O)=[CH:6][CH:5]=1)([CH3:3])[CH3:2].[CH3:17][N:18]([CH3:36])[C:19]1[CH:24]=[CH:23][C:22]([CH2:25][NH:26][C:27]2[CH:32]=[CH:31][C:30]([CH:33]([CH3:35])[CH3:34])=[CH:29][CH:28]=2)=[CH:21][CH:20]=1>>[CH3:17][N:18]([CH3:36])[C:19]1[CH:20]=[CH:21][C:22]([CH2:25][N:26]([C:27]2[CH:32]=[CH:31][C:30]([CH:33]([CH3:34])[CH3:35])=[CH:29][CH:28]=2)[C:14]([CH:11]2[C:12]3[C:7](=[CH:6][CH:5]=[C:4]([CH:1]([CH3:2])[CH3:3])[CH:13]=3)[CH2:8][CH2:9][CH2:10]2)=[O:16])=[CH:23][CH:24]=1

Participants

3

Reactant 2

HCID 17854306HCID 17854306, compoundHCID 21957887N-(4-(Dimethylamino)benzyl)-4-isopropylbenzenamine

Product 1

HCID 10162195HCID 10162195, compoundYield 28.4%

Procedure

By the reaction and treatment in the same manner as in Example 1 using 7-isopropyl-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (1.0 g) and [(4-dimethylaminophenyl)methyl](4-isopropylphenyl)amine (1.07 g) as starting materials, N-[(4-dimethylaminophenyl)methyl]-7-isopropyl-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.53 g) was obtained. melting point: 123-125° C.

Sources & evidence

ORD record
ord-312048a7c2d64726b0c0ceaa487cbd86
Source dataset
uspto-grants-2010_12
Patent number
US07855297B2

Reaction notes

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