1,2,3,4-Tetrahydro-1-naphthoic acid → N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide

Participants

Role	Name	HCID	Charge
Reactant	1,2,3,4-Tetrahydro-1-naphthoic acid	HCID 12598146	—
Reactant	N-((1-Ethyl-1H-pyrazol-4-yl)methyl)-4-isopropylaniline	HCID 21957909	—
Product	N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide	HCID 10222699	12.8%

Reaction Steps

By the reaction and treatment in the same manner as in Example 1 using 1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (0.5 g) and [(1-ethylpyrazol-4-yl)methyl](4-isopropylphenyl)amine (0.57 g) as starting materials, N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.12 g) was obtained. melting point: 75-76° C.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07855297B2
Source dataset	uspto-grants-2010_12
ORD ID	ord-54a29d787b924ec5a7580b94faccf72d
Source note	uspto-grants-2010_12