6-Methoxychroman-4-carboxylic acid → N-[(4-dimethylaminophenyl) methyl]-N-(4-isopropylphenyl)-6-methoxychroman-4-carboxamide

HRID 2265347Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2265347
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[O:9][CH2:8][CH2:7][CH:6]2[C:13]([OH:15])=O.[CH3:16][N:17]([CH3:35])[C:18]1[CH:23]=[CH:22][C:21]([CH2:24][NH:25][C:26]2[CH:31]=[CH:30][C:29]([CH:32]([CH3:34])[CH3:33])=[CH:28][CH:27]=2)=[CH:20][CH:19]=1>>[CH3:16][N:17]([CH3:35])[C:18]1[CH:19]=[CH:20][C:21]([CH2:24][N:25]([C:26]2[CH:31]=[CH:30][C:29]([CH:32]([CH3:33])[CH3:34])=[CH:28][CH:27]=2)[C:13]([CH:6]2[C:5]3[C:10](=[CH:11][CH:12]=[C:3]([O:2][CH3:1])[CH:4]=3)[O:9][CH2:8][CH2:7]2)=[O:15])=[CH:22][CH:23]=1

Komponenten

3

Edukt 2

HCID 202736706-Methoxychroman-4-carboxylic acidHCID 21957887N-(4-(Dimethylamino)benzyl)-4-isopropylbenzenamine

Produkt 1

HCID 10115381N-[(4-dimethylaminophenyl) methyl]-N-(4-isopropylphenyl)-6-methoxychroman-4-carboxamideAusbeute 25,2 %

Versuchsvorschrift

By the reaction and treatment in the same manner as in Example 1 using 6-methoxychroman-4-carboxylic acid (0.54 g) and [(4-dimethylaminophenyl)methyl](4-isopropylphenyl)amine (0.7 g) as starting materials, N-[(4-dimethylaminophenyl) methyl]-N-(4-isopropylphenyl)-6-methoxychroman-4-carboxamide (0.3 g) was obtained. melting point: 82-84° C.

Quellen und Nachweise

ORD-Eintrag
ord-158e0d4d3c68462c98c94f724beec85c
Quelldatensatz
uspto-grants-2010_12
Patentnummer
US07855297B2

Notizen zur Reaktion

Wird geladen…