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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2265359Generated: October 30, 2026

1,2,3,4-Tetrahydro-1-naphthoic acid → N-(4-butylphenyl)-N-[(4-dimethylaminophenyl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide

https://huagongshe.com/reaction/2265359

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2,3,4-Tetrahydro-1-naphthoic acidHCID 12598146—
Reactant(4-Butylphenyl)[(4-dimethylaminophenyl)methyl]amineHCID 21957943—
ProductN-(4-butylphenyl)-N-[(4-dimethylaminophenyl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamideHCID 1027502537.4%

Reaction Steps

By the reaction and treatment in the same manner as in Example 12 using 1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (0.45 g) and (4-butylphenyl)[(4-dimethylaminophenyl)-methyl]amine (0.6 g) as starting materials, N-(4-butylphenyl)-N-[(4-dimethylaminophenyl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.35 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07855297B2
Source datasetuspto-grants-2010_12
ORD IDord-ab7bd6c7879d48acb6674f457b79022b
Source noteuspto-grants-2010_12