Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-phenyl)-amine → HCID 10297328, compound

HRID 2265360Notes

Reaction equation

HRID 2265360 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH2:7][CH2:8][CH2:9][CH:10]2[C:13]([OH:15])=O)=[CH:5][CH:4]=1.[O:16]1[C:24]2[C:19](=[CH:20][C:21]([CH2:25][NH:26][C:27]3[CH:32]=[CH:31][C:30]([O:33][CH3:34])=[CH:29][CH:28]=3)=[CH:22][CH:23]=2)[O:18][CH2:17]1>>[O:16]1[C:24]2[C:19](=[CH:20][C:21]([CH2:25][N:26]([C:27]3[CH:32]=[CH:31][C:30]([O:33][CH3:34])=[CH:29][CH:28]=3)[C:13]([CH:10]3[C:11]4[C:6](=[CH:5][CH:4]=[C:3]([O:2][CH3:1])[CH:12]=4)[CH2:7][CH2:8][CH2:9]3)=[O:15])=[CH:22][CH:23]=2)[O:18][CH2:17]1

Participants

3

Reactant 2

HCID 964802Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-phenyl)-amineHCID 132774847-Methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid

Product 1

HCID 10297328HCID 10297328, compoundYield 9.3%

Procedure

By the reaction and treatment in the same manner as in Example 12 using 7-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (0.75 g) and [(1,3-dioxaindan-5-yl)methyl](4-methoxyphenyl)amine (0.93 g) as starting materials, N-[(1,3-dioxaindan-5-yl)methyl]-N-(4-methoxyphenyl)-7-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.15 g) was obtained.

Sources & evidence

ORD record
ord-f549bd9d20624c1096f0d3d390f309bc
Source dataset
uspto-grants-2010_12
Patent number
US07855297B2

Reaction notes

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