HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid → N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-6-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid | HCID 12790794 | — |
| Reactant | N-((1-Ethyl-1H-pyrazol-4-yl)methyl)-4-isopropylaniline | HCID 21957909 | — |
| Product | N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-6-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxamide | HCID 59597242 | 69.4% |
Reaction Steps
By the reaction and treatment in the same manner as in Example 4 using 6-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (0.31 g) and [(1-ethylpyrazol-4-yl)methyl](4-isopropylphenyl)amine (0.37 g) as starting materials, N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-6-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.45 g) was obtained. melting point: 111-113° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07855297B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-5290e4b91b5b43ea855ee917c78e4f72 |
| Source note | uspto-grants-2010_12 |