HRID2265385

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID17854482

未命名化合物

HCID21957909

未命名化合物

PRODUCTS

生成物

结构：CCn1cc(CN(C(=O)C2CCCc3ccc(OCc4ccccc4)cc32)c2ccc(C(C)C)cc2)cn1

HCID59597339

未命名化合物

收率 60.6%

PROCEDURE

实验过程

By the reaction and treatment in the same manner as in Example 4 using 7-benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (0.56 g) and [(1-ethylpyrazol-4-yl)methyl](4-isopropylphenyl)amine (0.49 g) as starting materials, 7-benzyloxy-N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.61 g) was obtained. melting point: 100-101° C.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-cdc2124b00ed40d4bf7b4efb84683e7d
来源数据集: uspto-grants-2010_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07855297B2
来源说明: uspto-grants-2010_12

反应 SMILES

[CH2:1]([O:8][C:9]1[CH:18]=[C:17]2[C:12]([CH2:13][CH2:14][CH2:15][CH:16]2[C:19](O)=[O:20])=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:22]([N:24]1[CH:28]=[C:27]([CH2:29][NH:30][C:31]2[CH:36]=[CH:35][C:34]([CH:37]([CH3:39])[CH3:38])=[CH:33][CH:32]=2)[CH:26]=[N:25]1)[CH3:23]>>[CH2:1]([O:8][C:9]1[CH:18]=[C:17]2[C:12]([CH2:13][CH2:14][CH2:15][CH:16]2[C:19]([N:30]([CH2:29][C:27]2[CH:26]=[N:25][N:24]([CH2:22][CH3:23])[CH:28]=2)[C:31]2[CH:32]=[CH:33][C:34]([CH:37]([CH3:38])[CH3:39])=[CH:35][CH:36]=2)=[O:20])=[CH:11][CH:10]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1