HCID 17854306, compound → HCID 59597356, compound

HRID 2265393Notes

Reaction equation

HRID 2265393 reaction equation
[CH:1]([C:4]1[CH:13]=[C:12]2[C:7]([CH2:8][CH2:9][CH2:10][CH:11]2[C:14]([OH:16])=O)=[CH:6][CH:5]=1)([CH3:3])[CH3:2].[CH2:17]([N:19]1[CH:23]=[C:22]([CH2:24][NH:25][C:26]2[CH:31]=[CH:30][C:29]([CH:32]([CH3:34])[CH3:33])=[CH:28][CH:27]=2)[CH:21]=[N:20]1)[CH3:18]>>[CH2:17]([N:19]1[CH:23]=[C:22]([CH2:24][N:25]([C:26]2[CH:27]=[CH:28][C:29]([CH:32]([CH3:33])[CH3:34])=[CH:30][CH:31]=2)[C:14]([CH:11]2[C:12]3[C:7](=[CH:6][CH:5]=[C:4]([CH:1]([CH3:2])[CH3:3])[CH:13]=3)[CH2:8][CH2:9][CH2:10]2)=[O:16])[CH:21]=[N:20]1)[CH3:18]

Participants

3

Reactant 2

HCID 17854306HCID 17854306, compoundHCID 21957909N-((1-Ethyl-1H-pyrazol-4-yl)methyl)-4-isopropylaniline

Product 1

HCID 59597356HCID 59597356, compoundYield 68.6%

Procedure

By the reaction and treatment in the same manner as in Example 12 using 7-isopropyl-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (0.33 g) and [(1-ethylpyrazol-4-yl)methyl](4-isopropylphenyl)amine (0.37 g) as starting materials, N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-7-isopropyl-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.46 g) was obtained.

Sources & evidence

ORD record
ord-13efb5d4977a4cbb9c8dfd10a9a32930
Source dataset
uspto-grants-2010_12
Patent number
US07855297B2

Reaction notes

Loading…