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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 226543Generated: October 25, 2026

4-Fluoro-2-(trifluoromethyl)aniline → HCID 57755026, compound

https://huagongshe.com/reaction/226543

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-2-(trifluoromethyl)anilineHCID 67853—
Reactant2-(3'-Fluoro-5-trifluoromethanesulfonyloxy-5'-trifluoromethyl-biphenyl-3-yl)-4-methyl-pentanoic acid methyl esterHCID 57754925—
ProductHCID 57755026HCID 57755026100%

Reaction Steps

The title compound was prepared in 100% yield from 2-(5′-fluoro-5-trifluoromethanesulfonyloxy-3′-trifluoromethyl-biphenyl-3-yl)-4-methyl-pentanoic acid methyl ester (prepared in Example 40, step (a)) and 4-fluoro-2-(trifluoromethyl)aniline under the conditions described in Example 37, step (b).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557244B2
Source datasetuspto-grants-2009_07
ORD IDord-b8eaff4f78d04a6da7323556b979dad8
Source noteuspto-grants-2009_07