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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2265431Generated: November 1, 2026

2h-1-Benzopyran-4-carboxylic acid,3,4-dihydro-8-(phenylmethoxy)- → 8-benzyloxy-N-[(4-dimethylaminophenyl)methyl]-N-(4-isopropylphenyl)chroman-4-carboxamide

https://huagongshe.com/reaction/2265431

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2h-1-Benzopyran-4-carboxylic acid,3,4-dihydro-8-(phenylmethoxy)-HCID 17854153—
ReactantN-(4-(Dimethylamino)benzyl)-4-isopropylbenzenamineHCID 21957887—
Product8-benzyloxy-N-[(4-dimethylaminophenyl)methyl]-N-(4-isopropylphenyl)chroman-4-carboxamideHCID 6718330398.5%

Reaction Steps

By the reaction and treatment in the same manner as in Example 12 using 8-benzyloxychroman-4-carboxylic acid (0.54 g) and [(4-dimethylaminophenyl)methyl](4-isopropylphenyl)amine (0.51 g) as starting materials, 8-benzyloxy-N-[(4-dimethylaminophenyl)methyl]-N-(4-isopropylphenyl)chroman-4-carboxamide (1 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07855297B2
Source datasetuspto-grants-2010_12
ORD IDord-8a1b8f9ee211447e932784cb94b4d215
Source noteuspto-grants-2010_12