HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[(4-Bromoanilino)methyl]-N,N-dimethylaniline → N-(4-bromophenyl)-N-[(4-dimethylaminophenyl)methyl]-7-fluoro-1,2,3,4-tetrahydronaphthalene-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[(4-Bromoanilino)methyl]-N,N-dimethylaniline | HCID 15174101 | — |
| Reactant | 7-Fluoro-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid | HCID 17854522 | — |
| Product | N-(4-bromophenyl)-N-[(4-dimethylaminophenyl)methyl]-7-fluoro-1,2,3,4-tetrahydronaphthalene-1-carboxamide | HCID 16679664 | 25.8% |
Reaction Steps
By the reaction and treatment in the same manner as in Example 12 using 7-fluoro-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (0.41 g) and (4-bromophenyl)[(4-dimethylaminophenyl)methyl]amine (0.64 g) as starting materials, N-(4-bromophenyl)-N-[(4-dimethylaminophenyl)methyl]-7-fluoro-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.26 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07855297B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-7b4fcc65e9724727a43e5d8ae0a6f8bf |
| Source note | uspto-grants-2010_12 |