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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2265470Generated: October 31, 2026

5-Benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid → HCID 67183935, compound

https://huagongshe.com/reaction/2265470

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acidHCID 11208318—
ReactantHCID 86639101HCID 86639101—
ProductHCID 67183935HCID 6718393599.8%

Reaction Steps

By the reaction and treatment in the same manner as in Example 12 using 5-benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (0.57 g) and (4-bromophenyl)[(4-dimethylaminophenyl)methyl]amide (0.61 g) as starting materials, 5-benzyloxy-N-(4-bromophenyl)-N-[(4-dimethylaminophenyl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide (1.14 g) was obtained. By the reaction and treatment in the same manner as in Example 133 using this compound, N-(4-bromophenyl)-N-[(dimethylaminophenyl)methyl]-5-hydroxy-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.23 g) was obtained. melting point: 218-220° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07855297B2
Source datasetuspto-grants-2010_12
ORD IDord-a32c8ce1305e4e51b6c47ba48f164154
Source noteuspto-grants-2010_12