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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2265512생성일: 2026년 10월 26일

2-(Chloromethyl)-5-methoxypyridine → N-(6-isopropylpyridin-3-yl)-N-({1-[(5-methoxypyridin-2-yl)methyl]pyrazol-4-yl}methyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide dihydrochloride

https://huagongshe.com/reaction/2265512

반응식

참여 물질

역할이름HCID투입량
반응물2-(Chloromethyl)-5-methoxypyridineHCID 14517153—
반응물N-(6-isopropylpyridin-3-yl)-N-[(pyrazol-4-yl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide hydrochlorideHCID 67183012—
생성물N-(6-isopropylpyridin-3-yl)-N-({1-[(5-methoxypyridin-2-yl)methyl]pyrazol-4-yl}methyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide dihydrochlorideHCID 6718309373.8%

반응 단계

By the reaction and treatment in the same manner as in Example 334 using N-(6-isopropylpyridin-3-yl)-N-[(pyrazol-4-yl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide hydrochloride (0.95 g) and 2-chloromethyl-5-methoxypyridine (0.83 g) as starting materials, N-(6-isopropylpyridin-3-yl)-N-({1-[(5-methoxypyridin-2-yl)methyl]pyrazol-4-yl}methyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide dihydrochloride (0.97 g) was obtained.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07855297B2
출처 데이터셋uspto-grants-2010_12
ORD IDord-d92a5ea43629443fb8edf0a1c6c90174
출처 메모uspto-grants-2010_12