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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2265577생성일: 2026년 10월 26일

2-(Chloromethyl)-4-methylpyridine hydrochloride → 5-benzyloxy-N-(6-methoxypyridin-3-yl)-N-({1-[(4-methylpyridin-2-yl)methyl]pyrazol-4-yl}methyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide

https://huagongshe.com/reaction/2265577

반응식

참여 물질

역할이름HCID투입량
반응물2-(Chloromethyl)-4-methylpyridine hydrochlorideHCID 20061071—
반응물5-benzyloxy-N-(6-methoxypyridin-3-yl)-N-[(pyrazol-4-yl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamideHCID 59597415—
생성물5-benzyloxy-N-(6-methoxypyridin-3-yl)-N-({1-[(4-methylpyridin-2-yl)methyl]pyrazol-4-yl}methyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamideHCID 5959721078.2%

반응 단계

By the reaction and treatment in the same manner as in Example 271 using 5-benzyloxy-N-(6-methoxypyridin-3-yl)-N-[(pyrazol-4-yl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.94 g) and 2-chloromethyl-4-methylpyridine hydrochloride (0.71 g) as starting materials, 5-benzyloxy-N-(6-methoxypyridin-3-yl)-N-({1-[(4-methylpyridin-2-yl)methyl]pyrazol-4-yl}methyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.90 g) was obtained.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07855297B2
출처 데이터셋uspto-grants-2010_12
ORD IDord-0b52c30a3cd44a618bacda3646c54254
출처 메모uspto-grants-2010_12