Formic Acid → HCID 11037698, compound

Participants

Reaction Steps

CDCA (II) (15.0 g, 38.27 mmol) was dissolved in 83 ml of tetrahydrofuran and treated with 18 drops of 70% HClO4. Formic acid (50 ml) was then added dropwise in 40 min and the resulting mixture was reacted at 54° C. for 8 h. The mixture was then concentrated under vacuum and the residue was taken up in water. The white precipitate was filtered, washed several times with water, triturated in water at 5° C. for 20 min, and dried under high vacuum to obtain 16.5 g (36.83 mmol, 96%) of pure compound (V).

Provenance & Evidence