HCID 59597487, compound → HCID 178515221, compound

HRID 2265855Notes

Reaction equation

HRID 2265855 reaction equation
F[C:2]1[CH:11]=[CH:10][C:9]2[NH:8][CH:7]=[C:6]3[C:12](=[O:21])[N:13]([C:15]4[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=4)[N:14]=[C:5]3[C:4]=2[N:3]=1.C(OC(C1C=NC2C(C=1[Cl:37])=NC(F)=CC=2)=O)C>>[Cl:37][C:4]1[C:9]2[NH:8][CH:7]=[C:6]3[C:12](=[O:21])[N:13]([C:15]4[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=4)[N:14]=[C:5]3[C:10]=2[CH:11]=[CH:2][N:3]=1

Participants

3

Reactant 2

HCID 59597487HCID 59597487, compoundHCID 178515199HCID 178515199, compound

Product 1

HCID 178515221HCID 178515221, compound

Procedure

The title compound was prepared following the procedure described in Step 3 for synthesis for 5a using 15 instead of 4a. 1H-NMR (DMSO-d6) δ (ppm): 7.16 (1H, m), 7.44 (2H, dd, J=8.6, 7.6 Hz), 8.09 (1H, d, J=5.3 Hz), 8.14 (2H, dd, J=8.5, 1.1 Hz), 8.37 (1H, d, J=5.2 Hz), 8.51 (1H, s). m/z 297.7 (MH+).

Sources & evidence

ORD record
ord-6b613c1506094efa87e18fea5a8d1c99
Source dataset
uspto-grants-2010_12
Patent number
US07858614B2

Reaction notes

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