HRID2265883

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7497

N,N-Diethylethanolamine

C6H15NO

HCID68679430

未命名化合物

HCID68679822

Methyl 2-[4-(4-fluorophenoxy)benzenesulfonyl]-6-hydroxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylate

C23H20FNO6S

PRODUCTS

产物

HCID68679178

未命名化合物

PROCEDURE

实验过程

Methyl 2-[4-(4-fluorophenoxy)benzenesulfonyl]-6-hydroxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylate (3B) is reacted with 2-diethylaminoethanol by the method described under 3C.

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-2d048aaf0607429fa63d91e407becb7a
来源数据集: uspto-grants-2010_12
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US07858619B2
来源说明: uspto-grants-2010_12

反应SMILES

[F:1][C:2]1[CH:32]=[CH:31][C:5]([O:6][C:7]2[CH:12]=[CH:11][C:10]([S:13]([N:16]3[CH2:25][CH2:24][C:23]4[C:18](=[CH:19][CH:20]=[C:21]([OH:26])[CH:22]=4)[CH:17]3[C:27]([O:29][CH3:30])=[O:28])(=[O:15])=[O:14])=[CH:9][CH:8]=2)=[CH:4][CH:3]=1.[CH2:33]([N:35]([CH2:39][CH3:40])[CH2:36][CH2:37]O)[CH3:34].FC1C=CC(OC2C=CC(S(N3CCC4C(=CC=C(OCCCN5CCN(C)CC5)C=4)C3C(OC)=O)(=O)=O)=CC=2)=CC=1>>[CH2:33]([N:35]([CH2:39][CH3:40])[CH2:36][CH2:37][O:26][C:21]1[CH:22]=[C:23]2[C:18](=[CH:19][CH:20]=1)[CH:17]([C:27]([O:29][CH3:30])=[O:28])[N:16]([S:13]([C:10]1[CH:9]=[CH:8][C:7]([O:6][C:5]3[CH:4]=[CH:3][C:2]([F:1])=[CH:32][CH:31]=3)=[CH:12][CH:11]=1)(=[O:14])=[O:15])[CH2:25][CH2:24]2)[CH3:34]