Methyl 2-(4-hydroxypiperidin-1-yl)acetate → (4-Methoxy-piperidin-1-yl)-acetic acid methyl ester
Reaction equation
COC(=O)C[C@H]1[CH2:10][CH2:9][C@H:8]([O:11][CH3:12])[CH2:7][CH2:6]1.[CH3:14][O:15][C:16](=[O:25])[CH2:17][N:18]1CCC(O)CC1>>[CH3:14][O:15][C:16](=[O:25])[CH2:17][N:18]1[CH2:6][CH2:7][CH:8]([O:11][CH3:12])[CH2:9][CH2:10]1Participants
3
Procedure
The title compound can be prepared in accordance with the general method of intermediate B, step 3 from (4-hydroxy-piperidin-1-yl)-acetic acid methyl ester.
Sources & evidence
- ORD record
- ord-68854e0d22e8448581a27d3605761c69
- Source dataset
- uspto-grants-2010_12
- Patent number
- US07858630B2
Reaction notes
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