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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2266336Generated: October 26, 2026

5-(2-Chlorophenyl)-4-(4-chlorophenyl)-2-hydrazinylpyridine → 6-(2-chlorophenyl)-7-(4-chlorophenyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

https://huagongshe.com/reaction/2266336

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(2-Chlorophenyl)-4-(4-chlorophenyl)-2-hydrazinylpyridineHCID 57799387—
Reactant6-(2-chlorophenyl)-7-(4-chlorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-oneHCID 59641677—
Product6-(2-chlorophenyl)-7-(4-chlorophenyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-oneHCID 5779941488%

Reaction Steps

The title compound (190 mg, 88% yield) as a yellow foam was prepared from 5-(2-chlorophenyl)-4-(4-chlorophenyl)-2-hydrazinylpyridine (200 mg, 0.61 mmol) in a manner analogous to that in which 6-(2-chlorophenyl)-7-(4-chlorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one (Example 1G) was prepared. HPLC/MS: retention time=3.83 min, [M+H]+=356.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858639B2
Source datasetuspto-grants-2010_12
ORD IDord-16be320cfe6541339808cfc8f132f377
Source noteuspto-grants-2010_12