Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Orcinol | HCID 10436 | — |
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-Amino-5-methylphenol | HCID 3018667 | — |
Reaction Steps
A mixture of 5-methylbenzene-1,3-diol (6.0 g), ammonium chloride (3.0 g), water (9.0 mL), and ammonium hydroxide (6.8 mL, 33% in water) were sealed in a bomb and heated at 180° C. for 17 hours. The mixture was cooled to room temperature and the resulting precipitate collected by filtration. Crystallisation from water gave title compound, 1.7 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07858640B2 |
|---|
| Source dataset | uspto-grants-2010_12 |
|---|
| ORD ID | ord-564672e043ac4773b92b6d355a358f16 |
|---|
| Source note | uspto-grants-2010_12 |
|---|
