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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2266440Generated: November 1, 2026

Dimethylformamide → HCID 68781992, compound

https://huagongshe.com/reaction/2266440

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantPotassium CarbonateHCID 11430—
ReactantMethyl bromoacetateHCID 60984—
ReactantHCID 136335909HCID 136335909—
SolventDichloromethaneHCID 6344—
ProductHCID 68781992HCID 68781992—

Reaction Steps

A mixture of 8-chloro-3-(4-chlorophenylsulfanyl)-2,4-dimethylquinolin-5-ol (0.050 μg), N,N-dimethylformamide (2.0 mL), potassium carbonate (0.059 g) and bromoacetic acid methyl ester (0.031 g) was stirred at room temperature for 15 hours. The mixture was diluted with dichloromethane and this solution was washed with water and then dried over magnesium sulfate. The solvent was removed under reduced pressure to afford title compound as brown solid, 0.11 g.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858640B2
Source datasetuspto-grants-2010_12
ORD IDord-01b9e1d2188b485f8509eb036cca8099
Source noteuspto-grants-2010_12