Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | 1-(tert-Butyldimethylsilyloxy)-1-methoxyethene | HCID 4564491 | — |
| Reactant | HCID 86631434 | HCID 86631434 | — |
| Catalyst | Ferrocene-1,1'-bis-(diphenylphosphine) | HCID 635956 | — |
| Catalyst | Tris(dibenzylideneacetone) dipalladium | HCID 9832798 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 68782473 | HCID 68782473 | — |
Reaction Steps
A mixture of trifluoromethanesulfonic acid 8-chloro-3-(4-chlorophenoxy)-2,4-dimethylquinolin-5-yl ester (0.20 g), tert-butyl-(1-methoxyvinyloxy)dimethyl silane (0.40 g), sodium acetate (0.044 g), tris(dibenzylideneacetone) dipalladium (0.020 g) and 1,1′-bis(diphenylphospino) ferrocene (0)(0.012 g) in N,N-dimethylformamide (5.0 mL) was heated by microwave irradiation at 120° C. for 15 minutes. The mixture was purified by column chromatography on silica gel, eluting with a mixture of pentane and dichloromethane (9:1 to 0:1 by volume) to afford title compound as a yellow oil, 0.034 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07858640B2 |
|---|
| Source dataset | uspto-grants-2010_12 |
|---|
| ORD ID | ord-22d8216e2e554beea83283546c8a7436 |
|---|
| Source note | uspto-grants-2010_12 |
|---|
