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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2266489Generated: October 31, 2026

3-Amino-4-fluorophenol → 2-(4-chlorobenzyl)-N-(2-fluoro-5-hydroxyphenyl)-3-oxobutyramide

https://huagongshe.com/reaction/2266489

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-4-fluorophenolHCID 13519180—
ReactantHCID 86631436HCID 86631436—
Product2-(4-chlorobenzyl)-N-(2-fluoro-5-hydroxyphenyl)-3-oxobutyramideHCID 86631437—

Reaction Steps

The title compound was prepared by the method of Preparation 34b using 3-amino-4-fluorophenol and 2-(4-chlorobenzyl)-3-oxothiobutyric acid S-tert-butyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858640B2
Source datasetuspto-grants-2010_12
ORD IDord-91ffc770260c4697ac848c88968630b1
Source noteuspto-grants-2010_12