4-Fluorobenzyl bromide → HCID 86631447, compound
Reaction equation
Br[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([F:9])=[CH:5][CH:4]=1.[C:10]([S:14][C:15](=[O:20])[CH2:16][C:17](=[O:19])[CH3:18])([CH3:13])([CH3:12])[CH3:11]>>[C:10]([S:14][C:15](=[O:20])[CH:16]([CH2:2][C:3]1[CH:8]=[CH:7][C:6]([F:9])=[CH:5][CH:4]=1)[C:17](=[O:19])[CH3:18])([CH3:13])([CH3:11])[CH3:12]Participants
3
Procedure
The title compound was prepared by the method of Preparation 34a using 1-bromomethyl-4-fluorobenzene and 3-oxothiobutyric acid S-tert-butyl ester.
Sources & evidence
- ORD record
- ord-27adc3657e36413d9322ca6cd73738ef
- Source dataset
- uspto-grants-2010_12
- Patent number
- US07858640B2
Reaction notes
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