Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,4-Dichloro-5-fluoropyrimidine → N2,N4-bis(indol-6-yl)-5-fluoro-2,4-pyrimidinediamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,4-Dichloro-5-fluoropyrimidine | HCID 250705 | — |
| 반응물 | 6-Aminoindole | HCID 256096 | — |
| 생성물 | N2,N4-bis(indol-6-yl)-5-fluoro-2,4-pyrimidinediamine | HCID 11552202 | — |
반응 단계
In like manner to the preparation of N2,N4-bis(3-hydroxyphenyl)-5-fluoro-2,4-pyrimidinediamine, 2,4-dichloro-5-fluoropyrimidine and 6-aminoindole were reacted to yield N2,N4-bis(indol-6-yl)-5-fluoro-2,4-pyrimidinediamine. LCMS: ret. time: 22.39 min.; purity: 85%; MS (m/e): 359 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07557210B2 |
| 출처 데이터셋 | uspto-grants-2009_07 |
| ORD ID | ord-681e3fb846c74604ad69e6604b32bae8 |
| 출처 메모 | uspto-grants-2009_07 |