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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2266580Generated: October 30, 2026

Butanethioic acid, 3-oxo-, S-(1,1-dimethylethyl) ester → 2-(2-chloro-4-fluorobenzyl)-3-oxothiobutyric acid S-tert-butyl Ester

https://huagongshe.com/reaction/2266580

Reaction equation

Participants

RoleNameHCIDCharge
ReactantButanethioic acid, 3-oxo-, S-(1,1-dimethylethyl) esterHCID 140007—
Reactant1-(Bromomethyl)-2-chloro-4-fluorobenzeneHCID 2725062—
Product2-(2-chloro-4-fluorobenzyl)-3-oxothiobutyric acid S-tert-butyl EsterHCID 86631454—

Reaction Steps

The title compound was prepared by the method of Preparation 34a using 1-bromomethyl-2-chloro-4-fluorobenzene and 3-oxothiobutyric acid S-tert-butyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858640B2
Source datasetuspto-grants-2010_12
ORD IDord-c1a2e392d5fe41068188dc5557652c21
Source noteuspto-grants-2010_12