Methyl 3-oxovalerate → 2-(4-ethanesulfonylbenzyl)-3-oxopentanoic Acid Methyl Ester
Reaction equation
Br[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([CH2:12][CH3:13])(=[O:11])=[O:10])=[CH:5][CH:4]=1.[CH3:14][O:15][C:16](=[O:22])[CH2:17][C:18](=[O:21])[CH2:19][CH3:20]>>[CH3:14][O:15][C:16](=[O:22])[CH:17]([CH2:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([CH2:12][CH3:13])(=[O:11])=[O:10])=[CH:5][CH:4]=1)[C:18](=[O:21])[CH2:19][CH3:20]Participants
3
Procedure
The title compound was prepared by the method of Preparation 34a using 1-bromomethyl-4-ethanesulfonylbenzene and 3-oxopentanoic acid methyl ester.
Sources & evidence
- ORD record
- ord-fecaa50c772449c28f434f583580bb06
- Source dataset
- uspto-grants-2010_12
- Patent number
- US07858640B2
Reaction notes
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